Why Estheticians Love Beta Glucan

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Why Estheticians Love Beta Glucan (And Why It Should Be in Your Routine) | Skin & Soul
Ingredients

Why Estheticians Love Beta Glucan (And Why It Should Be in Your Routine)

By Nicole Mazza, Licensed Esthetician  |  July 2026  |  6 min read

If you have been following the skincare world for any amount of time, you have probably heard a lot about hyaluronic acid. And it is a great ingredient. But there is one that I reach for even more often in my formulations, and that most people have not heard nearly enough about: beta glucan. Let me change that.

What Is Beta Glucan?

Beta glucan is a naturally occurring polysaccharide — a type of sugar molecule — derived most commonly from oats, yeast, and certain mushrooms. It has been used in medical research for decades because of its ability to support immune response and wound healing. In skincare, it made its way from dermatology clinics to product formulations because the same properties that make it useful medically make it exceptional for the skin.

The molecule is large enough to form a protective film on the skin's surface, but also has smaller fractions that can penetrate into the deeper layers of the epidermis. This is one of the things that makes it stand out from other humectants — it works on multiple levels simultaneously.

What Beta Glucan Actually Does for Skin

Beta glucan does a lot. Here is what the research actually supports:

Hydration that outperforms hyaluronic acid. In side-by-side studies, beta glucan has been shown to provide superior moisture retention compared to hyaluronic acid. It penetrates more effectively and holds hydration for longer because of how it binds to receptors in the skin (specifically Langerhans cells, which are part of the skin's immune network). The result is visible plumping and a supple texture that does not feel tacky or sticky.

Accelerated wound healing. Beta glucan activates macrophages — immune cells that clear debris and kick off the repair process. This is why it is used in wound care and why it is particularly valuable in post-treatment skincare. After any procedure that creates trauma to the skin (peels, microneedling, laser), beta glucan can meaningfully accelerate the recovery process.

Potent anti-inflammatory activity. Chronic low-grade inflammation is one of the main drivers of premature aging and sensitized skin. Beta glucan works as a biological response modifier — it modulates the inflammatory response rather than simply suppressing it. For acne-prone skin, sensitized skin, or skin that reacts easily, this is a significant benefit.

Antioxidant support. Beta glucan has antioxidant activity that helps protect the skin from free radical damage, which means it contributes to anti-aging protection alongside its other functions.

Barrier strengthening. By supporting the skin's natural repair mechanisms and reducing inflammation, beta glucan helps maintain and restore the integrity of the skin barrier over time.

Beta Glucan vs. Hyaluronic Acid: What's the Difference?

Property Beta Glucan Hyaluronic Acid
Primary function Humectant + healing + anti-inflammatory Humectant
Moisture retention Superior in studies Strong, draws water from environment
Skin penetration Multiple molecular sizes; penetrates well Depends heavily on molecular weight
Anti-inflammatory Yes — significant Minimal
Post-treatment use Ideal — supports wound healing Helpful but less targeted
Sensitivity compatibility Excellent — very well tolerated Generally well tolerated
Texture on skin Silky, non-sticky Can feel tacky at higher concentrations

This is not an either/or — both ingredients can and should coexist in a routine. But if you have sensitive, reactive, or post-treatment skin, beta glucan should absolutely be in your lineup.

Why I Included It in Two of Our Products

Beta glucan is one of the first ingredients I knew I wanted in the Skin & Soul line. My clients skew sensitive and acne-prone, and I needed products that could deliver deep hydration without triggering inflammation or compromising a recovering barrier.

Beta glucan is featured in both our Revive Me Toning Mist and our Bounce Back Serum — because I wanted it working at every step of the routine, not just one.

In the Revive Me Toning Mist, beta glucan delivers an immediate hit of hydration and inflammation-calming support at the very first step after cleansing — when the barrier is most exposed and most in need of recovery. It preps the skin for everything that comes after and gives sensitive skin a calming buffer before you layer on actives.

In the Bounce Back Serum, beta glucan is working alongside other barrier-supportive ingredients to deeply hydrate and strengthen from within. The serum is where the real repair work happens, and beta glucan is central to that.

If you are using both together, you are getting beta glucan at two different stages of your routine — which means more sustained hydration, more consistent anti-inflammatory benefit, and better barrier support over time.

Who Should Be Using Beta Glucan?

Honestly, everyone can benefit from it. But it is especially important for:

  • Sensitive and reactive skin: Beta glucan calms redness and reduces reactivity without disrupting the barrier or causing purging
  • Post-treatment skin: After peels, laser, microneedling, or any procedure that creates controlled damage, beta glucan accelerates healing and reduces downtime
  • Acne-prone skin: Inflammatory acne responds well to anti-inflammatory support; beta glucan can help calm active breakouts without being comedogenic
  • Dry or dehydrated skin: The moisture-binding capacity of beta glucan is outstanding and works even in low-humidity environments
  • Aging skin: The antioxidant and wound-healing properties make beta glucan a strong anti-aging ingredient beyond just hydration

How to Use It

Beta glucan is an extremely well-tolerated ingredient with no known contraindications. You can use it morning and night, before or after actives, and it layers seamlessly under everything. There is no "too much" with beta glucan — it does not cause purging, does not increase photosensitivity, and is safe during pregnancy and nursing.

For the best results, layer your toner and serum while your skin is still slightly damp after cleansing. This maximizes absorption and gives the humectants more water to bind to.

Beta glucan is one of those ingredients I genuinely believe every person with skin should know about. Once you start using it, you will understand why estheticians keep recommending it. It just works — and it works for almost everyone.

About the Author

Nicole Mazza

Licensed Esthetician · Founder of Skin & Soul

Nicole is a licensed esthetician and the founder of Skin & Soul — a skincare studio and indie brand in Bushwick, Brooklyn. Her product line is Korean-inspired and formulated for sensitive and acne-prone skin, while her studio offers a range of beginner to advanced treatments with barrier health as the foundation of every service.

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